CNTD2 Polyclonal antibody

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  WB analysis using 31588-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 31588-1-AP (CNTD2 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

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  WB analysis of HepG2 using 31588-1-AP

  WB result of CNTD2 antibody (31588-1-AP; 1:1000; incubated at room temperature for 1.5 hours) with sh-Control and sh-CNTD2 transfected HepG2 cells.

• Featured Product
• KD/KO Validated

CNTD2 Polyclonal Antibody for WB, ELISA

Cat No. 31588-1-AP

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, ELISA

Synonyms

Homo sapiens (Human), Cyclin-P , Cyclin P

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Tested Applications

• Positive WB detected in: HepG2 cells

Recommended dilution

• Western Blot (WB): WB : 1:500-1:2000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

31588-1-AP targets CNTD2 in WB, ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: CNTD2 fusion protein Ag36380
• Full Name: cyclin N-terminal domain containing 2
• Calculated Molecular Weight: 33kDa
• Observed Molecular Weight: 25 kDa
• GenBank Accession Number: NM_024877
• Gene Symbol: CNTD2
• Gene ID (NCBI): 79935
• RRID: AB_3670047
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity Purification
• UNIPROT ID: Q9H8S5
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

CNTD2, also known as Cyclin N-terminal domain containing 2 or CCNP, is a protein that has been implicated in cancer cell proliferation and migration, particularly in colon and lung cancers . It is an atypical cyclin that contains a cyclin box domain, which is a characteristic feature of cyclin-dependent kinase (CDK) binding partners. CNTD2 is considered an atypical cyclin due to its structural specificities, which were revealed through the human genome sequence project (PMID: 30087414). The apparent molecular mass measured by SDS-PAGE is 25 kDa.