Product Information
19670-1-AP targets Collagen Type V in IHC, ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Reactivity | human, mouse, rat |
| Cited Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
Peptide Predict reactive species |
| Full Name | collagen, type V, alpha 2 |
| Calculated Molecular Weight | 145 kDa |
| GenBank Accession Number | NM_000393 |
| Gene Symbol | COL5A2 |
| Gene ID (NCBI) | 1290 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | P05997 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
COL5A2 belongs to the fibrillar collagen family. Type V collagen is a member of group I collagen (fibrillar forming collagen). It is a minor connective tissue component of nearly ubiquitous distribution. Type V collagen binds to DNA, heparan sulfate, thrombospondin, heparin, and insulin. Type V collagen is a key determinant in the assembly of tissue-specific matrices Defects in COL5A2 are a cause of Ehlers-Danlos syndrome type 1 (EDS1) which also known as Ehlers-Danlos syndrome gravis or severe classic type Ehlers-Danlos syndrome. This antibody is specific to COL5A2.
Publications
What published studies show
The Collagen Type V Polyclonal antibody (catalog no. 19670-1-AP), specific to COL5A2, has 1 citation. It was used in IHC in a study published in Current Medical Science (2022) investigating bioinformatics analysis and identification of potential genes associated with the pathogenesis and prognosis of gastric cancer. The research falls within the fields of oncology, specifically gastric cancer, and connective tissue biology.
| Species | Application | Title |
|---|---|---|
Curr Med Sci Bioinformatics Analysis and Identification of Potential Genes Associated with Pathogenesis and Prognosis of Gastric Cancer |
