Product Information
19670-1-AP targets Collagen Type V in IHC, ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Reactivity | human, mouse, rat |
| Cited Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
Peptide Predict reactive species |
| Full Name | collagen, type V, alpha 2 |
| Calculated Molecular Weight | 145 kDa |
| GenBank Accession Number | NM_000393 |
| Gene Symbol | COL5A2 |
| Gene ID (NCBI) | 1290 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | P05997 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
COL5A2 belongs to the fibrillar collagen family. Type V collagen is a member of group I collagen (fibrillar forming collagen). It is a minor connective tissue component of nearly ubiquitous distribution. Type V collagen binds to DNA, heparan sulfate, thrombospondin, heparin, and insulin. Type V collagen is a key determinant in the assembly of tissue-specific matrices Defects in COL5A2 are a cause of Ehlers-Danlos syndrome type 1 (EDS1) which also known as Ehlers-Danlos syndrome gravis or severe classic type Ehlers-Danlos syndrome. This antibody is specific to COL5A2.
