COPS3 Polyclonal antibody

• Featured Product
• KD/KO Validated

COPS3 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

Human, mouse, rat

Applications

WB, ELISA

Conjugate

Unconjugated

Cat no : 30494-1-AP

Synonyms

COPS3, CSN3, SGN3, Signalosome subunit 3

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Validation Data Gallery

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  WB analysis using 30494-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 30494-1-AP (COPS3 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours.

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  WB analysis of HeLa using 30494-1-AP

  WB result of COPS3 antibody (30494-1-AP; 1:2000; incubated at room temperature for 1.5 hours) with sh-Control and sh-COPS3 transfected HeLa cells.

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Tested Applications

• Positive WB detected in: HeLa cells, MCF-7 cells, mouse brain tissue, rat brain tissue

Recommended dilution

• Western Blot (WB): WB : 1:2000-1:10000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

30494-1-AP targets COPS3 in WB, ELISA applications and shows reactivity with Human, mouse, rat samples.

• Tested Reactivity: Human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: COPS3 fusion protein Ag32825
• Full Name: COP9 constitutive photomorphogenic homolog subunit 3 (Arabidopsis)
• Calculated Molecular Weight: 48 kDa
• Observed Molecular Weight: 40 kDa
• GenBank Accession Number: BC001891
• Gene Symbol: COPS3
• Gene ID (NCBI): 8533
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

COPS3 possesses kinase activity that phosphorylates regulators involved in signal transduction. It phosphorylates I kappa-Balpha, p105, and c-Jun. It acts as a docking site for complex-mediated phosphorylation. The gene is located within the Smith-Magenis syndrome region on chromosome 17.