COPS8/COP9 Antibody 1 Publications

Rabbit Polyclonal| Catalog number: 10089-2-AP

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Freight/Packing

Con: 43 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
mouse brain tissue

Positive IHC detected in:
mouse brain tissue, human gliomas tissue, mouse brain tissue

Recommended dilution:
WB : 1:500-1:1000
IHC : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
COP9 constitutive photomorphogenic homolog subunit 8 (Arabidopsis)

Calculated molecular weight:
23 kDa

Observed molecular weight:
23 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
COPS8

Synonyms
COP9, COP9 homolog, COPS8, CSN8, hCOP9, SGN8, Signalosome subunit 8
Background

COPS8 is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases.


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