Mouse CRTAM/CD355 Polyclonal antibody, PBS Only

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• Mouse CRTAM/CD355 Polyclonal antibody, PBS Only (32680-1-PBS)

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  WB analysis using 32680-1-AP (same clone as 32680-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 32680-1-AP (CRTAM/CD355 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 32680-1-PBS in a different storage buffer formulation.

CRTAM/CD355 Polyclonal Antibody for WB, Indirect ELISA

Cat No. 32680-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

mouse, rat

Applications

WB, Indirect ELISA

Synonyms

CD355, Class-I MHC-restricted T-cell-associated molecule, Crtam, Cytotoxic and regulatory T-cell molecule

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Product Information

32680-1-PBS targets CRTAM/CD355 in WB, Indirect ELISA applications and shows reactivity with mouse, rat samples.

• Tested Reactivity: mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  Recombinant protein

• Full Name: cytotoxic and regulatory T cell molecule
• Calculated Molecular Weight: 44 kDa
• Observed Molecular Weight: 70 kDa
• GenBank Accession Number: NM_001281954.1
• Gene Symbol: Crtam
• Gene ID (NCBI): 54698
• RRID: AB_3742702
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity Purification
• UNIPROT ID: Q149L7-1
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

Cytotoxic and regulatory T cell molecule (CRTAM, also known as CD355) is an immunoglobulin-superfamily transmembrane protein with V and C1-like Ig domains, which is involved in epithelial cell adhesion (PMID: 18329370; 20556794). CRTAM is critical to instruct the differentiation of CD4+ cytotoxic T cells (CTL) through the induction of eomesodermin and CTL-related genes (PMID: 26694968). It also regulates CD8+ T cell retention within the lymph node and eventually effector function (PMID: 19752223). The predicted molecular weight of CRTAM is 44 kDa. Due to glycosylation, the observed molecular weight of CRTAM can be apparent at ~80 kDa (PMID: 16300832).