Product Information
33679-1-PBS targets CRYL1 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Reactivity | human, mouse, rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag38269 Product name: Recombinant human CRYL1 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-319 aa of NM_015974.2 Sequence: MASSAAGCVVIVGSGVIGRSWAMLFASGGFQVKLYDIEQQQIRNALENIRKEMKLLEQAGSLKGSLSVEEQLSLISGCPNIQEAVEGAMHIQECVPEDLELKKKIFAQLDSIIDDRVILSSSTSCLMPSKLFAGLVHVKQCIVAHPVNPPYYIPLVELVPHPETAPTTVDRTHALMKKIGQCPMRVQKEVAGFVLNRLQYAIISEAWRLVEEGIVSPSDLDLVMSEGLGMRYAFIGPLETMHLNAEGMLSYCDRYSEGIKHVLQTFGPIPEFSRATAEKVNQDMCMKVPDDPEHLAARRQWRDECLMRLAKLKSQVQPQ Predict reactive species |
| Full Name | crystallin, lambda 1 |
| Calculated Molecular Weight | 35kDa，319aa |
| Observed Molecular Weight | 35 kDa |
| GenBank Accession Number | NM_015974.2 |
| Gene Symbol | CRYL1 |
| Gene ID (NCBI) | 51084 |
| RRID | AB_3743046 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity Purification |
| UNIPROT ID | Q9Y2S2 |
| Storage Buffer | PBS only, pH 7.3. |
| Storage Conditions | Store at -80°C. |
Background Information
CRYL1 (Crystallin Lambda 1) is a ubiquitously-expressed, dual-function protein that was first isolated from rabbit lens tissue. Human CRYL1 is encoded at chromosomal locus 13q12.11, contains two HCDH (3-hydroxyacyl-CoA dehydrogenase) domains, and is most abundant in liver and kidney, with only trace expression in peripheral-blood leukocytes and thymus. Further research showed that CRYL1 was expressed at lower levels in HCC tumors than in adjacent tissues, and this reduced expression was associated with advanced tumor staging, larger tumors, and decreased patient disease-free survival.
