|Positive WB detected in||mouse heart tissue, rat brain tissue|
|Positive IP detected in||mouse heart tissue|
|Western Blot (WB)||WB : 1:500-1:1000|
|Immunoprecipitation (IP)||IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB|
|Sample-dependent, check data in validation data gallery|
10346-1-AP targets CTBP2 in WB, IP, IF,ELISA applications and shows reactivity with human, mouse, rat samples.
|Tested Reactivity||human, mouse, rat|
|Cited Reactivity||gerbil, mouse, zebrafish|
|Host / Isotype||Rabbit / IgG|
|Immunogen||CTBP2 fusion protein Ag0352|
|Full Name||C-terminal binding protein 2|
|Calculated molecular weight||49 kDa|
|Observed molecular weight||49 kDa|
|GenBank accession number||BC002486|
|Gene ID (NCBI)||1488|
|Purification Method||Antigen affinity purification|
|Storage Buffer||PBS with 0.02% sodium azide and 50% glycerol pH 7.3.|
|Storage Conditions||Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.|
C-Terminal binding protein 2 (CTBP2) is a transcriptional repressor. It contains a NAD+ binding domain similar to NAD+-dependent 2-hydroxyacid dehydrogenases. This protein is thought to bind to the C-terminus of the adenovirus E1A proteins. Studies in mice suggested that this protein is involved in transcriptional repression. CTBP2 is expressed in all tissues tested, with a higher level of expression in the heart, skeletal muscle, and pancreas. The gene of CTBP2 is mapped to human chromosome 21q21.3.
Genet Mol Res
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