Validation Data Gallery
|Positive WB detected in||mouse brain tissue, mouse heart tissue, rat brain tissue|
|Positive IP detected in||mouse heart tissue|
|Positive IF detected in||HeLa cells|
|Western Blot (WB)||WB : 1:1000-1:4000|
|Immunoprecipitation (IP)||IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB|
|Immunofluorescence (IF)||IF : 1:1000-1:4000|
|Sample-dependent, check data in validation data gallery|
10346-1-AP targets CTBP2 in WB, IP, IF, ELISA applications and shows reactivity with human, mouse, rat samples.
|Tested Reactivity||human, mouse, rat|
|Cited Reactivity||mouse, gerbil, zebrafish|
|Host / Isotype||Rabbit / IgG|
|Immunogen||CTBP2 fusion protein Ag0352|
|Full Name||C-terminal binding protein 2|
|Calculated molecular weight||49 kDa|
|Observed molecular weight||49 kDa|
|GenBank accession number||BC002486|
|Gene ID (NCBI)||1488|
|Purification Method||Antigen affinity purification|
|Storage Buffer||PBS with 0.02% sodium azide and 50% glycerol pH 7.3.|
|Storage Conditions||Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.|
C-Terminal binding protein 2 (CTBP2) is a transcriptional repressor. It contains a NAD+ binding domain similar to NAD+-dependent 2-hydroxyacid dehydrogenases. This protein is thought to bind to the C-terminus of the adenovirus E1A proteins. Studies in mice suggested that this protein is involved in transcriptional repression. CTBP2 is expressed in all tissues tested, with a higher level of expression in the heart, skeletal muscle, and pancreas. The gene of CTBP2 is mapped to human chromosome 21q21.3.
Hair cell identity establishes labeled lines of directional mechanosensation.
Tonotopic variation in the calcium dependence of neurotransmitter release and vesicle pool replenishment at mammalian auditory ribbon synapses.
Specific Influences of Early Acoustic Environments on Cochlear Hair Cells in Postnatal Mice.
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MicroRNA-200 family members are weakly expressed in the neurosensory epithelia of the developing zebrafish (Danio rerio) inner ear.