CXCR5 Recombinant monoclonal antibody, PBS Only

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  WB analysis using 84639-2-RR (same clone as 84639-2-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 84639-2-RR (CXCR5 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84639-2-PBS in a different storage buffer formulation.

CXCR5 Uni-rAb^® Recombinant Antibody for WB, Indirect ELISA

Cat No. 84639-2-PBS

Clone No.241777A10

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Synonyms

CXCR 5, CXC R5, CD185, Burkitt lymphoma receptor 1, BLR1

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Product Information

84639-2-PBS targets CXCR5 in WB, Indirect ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen:

  Peptide

• Full Name: chemokine (C-X-C motif) receptor 5
• Calculated Molecular Weight: 372 aa, 42 kDa
• Observed Molecular Weight: 33 kDa
• GenBank Accession Number: BC110352
• Gene Symbol: CXCR5
• Gene ID (NCBI): 643
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purfication
• UNIPROT ID: P32302
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

Initially discovered in 1992 as Burkitt's lymphoma receptor 1, CXCR5 (chemokine receptor 5, also known as CD185) is a seven-transmembrane G protein-coupled receptor (GPCR) protein (PMID: 32994482). CXCR5 is essential for naïve B-cell migration to and maturation in the lymph nodes and spleen, as well as for cluster of differentiation 4 T-cell (TFH and TCM) homing and interaction with B cells (PMID: 21471443). Moreover, CXCR5 is involved in the regulation of neural stem cells (NSC) and neuronal regeneration in the mouse brain, neuronal differentiation, neurogenesis, gliogenesis, and synaptogenesis (PMID: 37460877).