CXXC5 Recombinant monoclonal antibody, PBS Only

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  WB analysis using 83940-7-RR (same clone as 83940-7-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 83940-7-RR (CXXC5 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83940-7-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 83940-7-RR

  Biolayer interferometry (BLl) kinetic assays of 83940-7-RR against Human CXXC5 were performed. The affinity constant is 5.73 nM.

CXXC5 Uni-rAb^® Recombinant Antibody for WB, Indirect ELISA

Cat No. 83940-7-PBS

Clone No.241034A6

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Synonyms

Putative MAPK-activating protein PM08, HSPC195, CXXC-type zinc finger protein 5, CXXC finger 5, CF5

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Product Information

83940-7-PBS targets CXXC5 in WB, Indirect ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen:

  CatNo: Ag9733

  Product name: Recombinant human CXXC5 protein

  Source: e coli.-derived, PGEX-4T

  Tag: GST

  Domain: 1-227 aa of BC017439

  Sequence: MMGGESADKATAAAAAASLLANGHDLAAAMAVDKSNPTSKHKSGAVASLLSKAERATELAAEGQLTLQQFAQSTEMLKRVVQEHLPLMSEAGAGLPDMEAVAGAEALNGQSDFPYLGAFPINPGLFIMTPAGVFLAESALHMAGLAEYPMQGELASAISSGKKKRKRCGMCAPCRRRINCEQCSSCRNRKTGHQICKFRKCEELKKKPSAALEKVMLPTGAAFRWFQ

• Full Name: CXXC finger 5
• Calculated Molecular Weight: 322aa,33 kDa; 227aa,24 kDa
• Observed Molecular Weight: 33-40 kDa
• GenBank Accession Number: BC017439
• Gene Symbol: CXXC5
• Gene ID (NCBI): 51523
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purfication
• UNIPROT ID: Q7LFL8
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

CXXC5 (CXXC-type zinc finger protein 5) is also named as HSPC195, RINF and TCCCIA00297.CXXC5 is a member of the CXXC-type zinc-finger protein family. CXXC5 is a short protein (322 amino acids in length) that does not have any catalytic domain, but is able to bind to DNA and act as a transcription factor and epigenetic factor through protein-protein interactions. In addition, CXXC5 is capable of regulating various signal transduction processes, including the TGF-β, Wnt and ATM-p53 pathways, thereby acting as a novel and crucial signaling coordinator. CXXC5 plays an important role in embryonic development and adult tissue homeostasis by regulating cell proliferation, differentiation and apoptosis (PMID: 30479059). CXXC5 has two isoforms of 33 kDa and 24 kDa (PMID: 25805812).