CXorf21 Polyclonal antibody, PBS Only

• Home
• Products
• Primary Antibodies
• CXorf21 Polyclonal antibody, PBS Only (30244-1-PBS)

• 

  WB analysis using 30244-1-AP (same clone as 30244-1-PBS)

  THP-1 cells were subjected to SDS PAGE followed by western blot with 30244-1-AP (CXorf21 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 30244-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse skin using 30244-1-AP (same clone as 30244-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse skin tissue slide using 30244-1-AP (CXorf21 antibody) at dilution of 1:500 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 30244-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse skin using 30244-1-AP (same clone as 30244-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse skin tissue slide using 30244-1-AP (CXorf21 antibody) at dilution of 1:500 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 30244-1-PBS in a different storage buffer formulation.

• 

  IHC staining of rat skin using 30244-1-AP (same clone as 30244-1-PBS)

  Immunohistochemical analysis of paraffin-embedded rat skin tissue slide using 30244-1-AP (CXorf21 antibody) at dilution of 1:500 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 30244-1-PBS in a different storage buffer formulation.

• 

  IHC staining of rat skin using 30244-1-AP (same clone as 30244-1-PBS)

  Immunohistochemical analysis of paraffin-embedded rat skin tissue slide using 30244-1-AP (CXorf21 antibody) at dilution of 1:500 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 30244-1-PBS in a different storage buffer formulation.

• 

  IHC staining of rat stomach using 30244-1-AP (same clone as 30244-1-PBS)

  Immunohistochemical analysis of paraffin-embedded rat stomach tissue slide using 30244-1-AP (CXorf21 antibody) at dilution of 1:500 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 30244-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human cervical cancer using 30244-1-AP (same clone as 30244-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human cervical cancer tissue slide using 30244-1-AP (CXorf21 antibody) at dilution of 1:500 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 30244-1-PBS in a different storage buffer formulation.

• 

  IF Staining of U2OS using 30244-1-AP (same clone as 30244-1-PBS)

  Immunofluorescent analysis of (-20°C Methanol) fixed U2OS cells using CXorf21 antibody (30244-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 30244-1-PBS in a different storage buffer formulation.

• 

  IF Staining of U-251 using 30244-1-AP (same clone as 30244-1-PBS)

  Immunofluorescent analysis of (-20°C Ethanol) fixed U-251 cells using CXorf21 antibody (30244-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L), CL594-phalloidin (red). This data was developed using the same antibody clone with 30244-1-PBS in a different storage buffer formulation.

CXorf21 Polyclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA

Cat No. 30244-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, IF/ICC, Indirect ELISA

Synonyms

TASL, TLR adapter interacting with SLC15A4 on the lysosome

---

Product Information

30244-1-PBS targets CXorf21 in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  CatNo: Ag32773

  Product name: Recombinant human CXorf21 protein

  Source: e coli.-derived, PGEX-4T

  Tag: GST

  Domain: 1-301 aa of BC020611

  Sequence: MLSEGYLSGLEYWNDIHWSCASYNEQVAGEKEEETNSVATLSYSSVDETQVRSLYVSCKSSGKFISSVHSRESQHSRSQRVTVLQTNPNPVFESPNLAAVEICRDASRETYLVPSSCKSICKNYNDLQIAGGQVMAINSVTTDFPSESSFEYGPLLKSSEIPLPMEDSISTQPSDFPQKPIQRYSSYWRITSIKEKSSLQMQNPISNAVLNEYLEQKVVELYKQYIMDTVFHDSSPTQILASELIMTSVDQISLQVSREKNLETSKARDIVFSRLLQLMSTEITEISTPSLHISQYSNVNP

• Full Name: chromosome X open reading frame 21
• Observed Molecular Weight: 34 kDa
• GenBank Accession Number: BC020611
• Gene Symbol: CXorf21
• Gene ID (NCBI): 80231
• RRID: AB_3086276
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: Q9HAI6
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

CXorf21 (Chromosome X open reading frame 21) is also named as TASL and TLR adapter interacting with SLC15A4 on the lysosome. CXorf21 is an innate immune adapter that mediates the recruitment and activation of IRF5 downstream of endolysosomal toll-like receptors TLR7, TLR8 and TLR9 (PMID:32433612). CXorf21 plays a role in the regulation of endolysosomal pH in immune cells such as B-cells, dendritic cells and monocytes (PMID: 31001245). CXorf21 is a mediator of the X-chromosome gene dose-dependent increased risk of SLE in females (PMID: 31695690).