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CYP11B2 Polyclonal antibody, PBS Only (20968-1-PBS)

Filter: AllWBIHCIF/ICC

WB analysis using 20968-1-AP (same clone as 20968-1-PBS)
pig adrenal gland tissue were subjected to SDS PAGE followed by western blot with 20968-1-AP (CYP11B2 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 20968-1-PBS in a different storage buffer formulation.
WB analysis of SKOV-3 using 20968-1-AP (same clone as 20968-1-PBS)
SKOV-3 cells were subjected to SDS PAGE followed by western blot with 20968-1-AP (CYP11B2 Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 20968-1-PBS in a different storage buffer formulation.
IHC staining of human adrenal gland using 20968-1-AP (same clone as 20968-1-PBS)
Immunohistochemical analysis of paraffin-embedded human adrenal gland tissue slide using 20968-1-AP (CYP11B2 antibody) at dilution of 1:100 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 20968-1-PBS in a different storage buffer formulation.
IHC staining of human adrenal gland using 20968-1-AP (same clone as 20968-1-PBS)
Immunohistochemical analysis of paraffin-embedded human adrenal gland tissue slide using 20968-1-AP (CYP11B2 antibody) at dilution of 1:100 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 20968-1-PBS in a different storage buffer formulation.
IHC staining of human kidney using 20968-1-AP (same clone as 20968-1-PBS)
Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 20968-1-AP (CYP11B2 Antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 20968-1-PBS in a different storage buffer formulation.
IHC staining of human kidney using 20968-1-AP (same clone as 20968-1-PBS)
Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 20968-1-AP (CYP11B2 Antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 20968-1-PBS in a different storage buffer formulation.
IHC staining of human hepatocirrhosis using 20968-1-AP (same clone as 20968-1-PBS)
Immunohistochemical analysis of paraffin-embedded human hepatocirrhosis tissue slide using 20968-1-AP (CYP11B2 Antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 20968-1-PBS in a different storage buffer formulation.
IHC staining of human hepatocirrhosis using 20968-1-AP (same clone as 20968-1-PBS)
Immunohistochemical analysis of paraffin-embedded human hepatocirrhosis tissue slide using 20968-1-AP (CYP11B2 Antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 20968-1-PBS in a different storage buffer formulation.
IHC staining of human liver cancer using 20968-1-AP (same clone as 20968-1-PBS)
Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 20968-1-AP (CYP11B2 Antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 20968-1-PBS in a different storage buffer formulation.
IHC staining of human liver cancer using 20968-1-AP (same clone as 20968-1-PBS)
Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 20968-1-AP (CYP11B2 Antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 20968-1-PBS in a different storage buffer formulation.
IF Staining of SKOV-3 using 20968-1-AP (same clone as 20968-1-PBS)
Immunofluorescent analysis of SKOV-3 cells using 20968-1-AP (CYP11B2 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 20968-1-PBS in a different storage buffer formulation.

CYP11B2 Polyclonal antibody, PBS Only

Name: CYP11B2 Polyclonal antibody, PBS Only
Brand: Proteintech
SKU: 20968-1-PBS

CYP11B2 Polyclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA

Cat No. 20968-1-PBS

Review Product

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, pig

Applications

WB, IHC, IF/ICC, Indirect ELISA

Synonyms

Formulation: PBS Only

PBS, Azide, Glycerol

Conjugate: Unconjugated

Size/Concentration:

-/ -

Freight/Packing: -

Quantity

- +

Request bulk or custom quote

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Overview

Tested Applications
Product Information

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MSDS SDS

Product Information

20968-1-PBS targets CYP11B2 in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse, pig samples.

Tested Reactivity	human, mouse, pig
Host / Isotype	Rabbit / IgG
Class	Polyclonal
Type	Antibody
Immunogen	Peptide Predict reactive species
Full Name	cytochrome P450, family 11, subfamily B, polypeptide 2
Calculated Molecular Weight	58 kDa
Observed Molecular Weight	48-50 kDa
GenBank Accession Number	NM_000498
Gene Symbol	CYP11B2
Gene ID (NCBI)	1585
RRID	AB_2878777
Conjugate	Unconjugated
Form	Liquid
Purification Method	Antigen affinity purification
UNIPROT ID	P19099
Storage Buffer	PBS only, pH 7.3.
Storage Conditions	Store at -80°C.

Background Information

CYP11B2 (Cytochrome P450 11B2), also known as aldosterone synthase, is a member of the cytochrome P450 superfamily of enzymes. CYP11B2 can only catalyze 11-deoxycorticosterone oxidation to produce corticosterone and further hydroxylation to ALD. CYP11B2 is an enzyme required for cortisol biosynthesis and is specifically expressed in aldosterone-producing tissue of the adrenal cortex and is overexpressed in aldosterone-producing adenomas (APA).