CYP11B2 Recombinant monoclonal antibody, PBS Only

• 

  WB analysis of SKOV-3 using 83930-1-RR (same clone as 83930-1-PBS)

  SKOV-3 cells were subjected to SDS PAGE followed by western blot with 83930-1-RR (CYP11B2 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83930-1-PBS in a different storage buffer formulation.

CYP11B2 Uni-rAb^® Recombinant Antibody for WB, ELISA

Cat No. 83930-1-PBS

Clone No.240811E7

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, ELISA

Synonyms

240811E7, ALDOS, Aldosterone-synthesizing enzyme, Corticosterone 18-monooxygenase, CYP11B2, CPN2

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Product Information

83930-1-PBS targets CYP11B2 in WB, ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen:

  Peptide

• Full Name: cytochrome P450, family 11, subfamily B, polypeptide 2
• Calculated Molecular Weight: 58 kDa
• Observed Molecular Weight: 58-60 kDa
• GenBank Accession Number: NM_000498
• Gene Symbol: CYP11B2
• Gene ID (NCBI): 1585
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purfication
• UNIPROT ID: P19099
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

CYP11B2 (Cytochrome P450 11B2), also known as aldosterone synthase, is a member of the cytochrome P450 superfamily of enzymes. CYP11B2 can only catalyze 11-deoxycorticosterone oxidation to produce corticosterone and further hydroxylation to ALD. CYP11B2 is an enzyme required for cortisol biosynthesis and is specifically expressed in aldosterone-producing tissue of the adrenal cortex and is overexpressed in aldosterone-producing adenomas (APA).