CYP2D6 Monoclonal antibody
CYP2D6 Monoclonal Antibody for IHC, WB,ELISA
Host / Isotype
Mouse / IgG2b
Cat no : 60297-1-Ig
|Positive WB detected in
|HepG2 cells, fetal human brain tissue
|Positive IHC detected in
|human liver cancer tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
|Western Blot (WB)
|WB : 1:500-1:2000
|IHC : 1:50-1:500
|It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
|Sample-dependent, check data in validation data gallery
60297-1-Ig targets CYP2D6 in WB, IHC,ELISA applications and shows reactivity with human samples.
|Host / Isotype
|Mouse / IgG2b
|CYP2D6 fusion protein Ag12605
|cytochrome P450, family 2, subfamily D, polypeptide 6
|Calculated molecular weight
|497 aa, 56 kDa
|Observed molecular weight
|GenBank accession number
|Gene ID (NCBI)
|Protein A purification
|PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
|Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.
CYP2D6(Cytochrome P450 2D6) is also named as CYP2DL1 and belongs to the cytochrome P450 family. It is a monooxygenase that involved in the metabolism of drugs such as antiarrhythmics, adrenoceptor antagonists, and tricyclic antidepressants. CYP2D6 is responsible for the metabolism of many drugs and environmental chemicals that it oxidizes. It has 2 isoforms produced by alternative splicing with the molecular weight of 56 kDa and 50 kDa.