Product Information
16302-1-PBS targets Claudin 15 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Reactivity | human, mouse, rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag9124 Product name: Recombinant human CLDN15 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-128 aa of BC010160 Sequence: MSMAVETFGFFMATVGLLMLGVTLPNSYWRVSTVHGNVITTNTIFENLWFSCATDSLGVYNCWEFPSMLALSGSTDSPASLSGGTGLLVRLMSIKGPCEGRRLASCRLSVRCKEAVCVQGIFRPAGHS Predict reactive species |
| Full Name | claudin 15 |
| Calculated Molecular Weight | 128aa,14 kDa; 228aa,24 kDa |
| Observed Molecular Weight | 24-26 kDa |
| GenBank Accession Number | BC010160 |
| Gene Symbol | Claudin 15 |
| Gene ID (NCBI) | 24146 |
| RRID | AB_3741880 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | P56746 |
| Storage Buffer | PBS only, pH 7.3. |
| Storage Conditions | Store at -80°C. |
Background Information
Claudins are a family of proteins that are the most important components of tight junctions, where they establish the paracellular barrier that controls the flow of molecules in the intercellular space between the cells of an epithelium. 23 claudins have been identified. They are small (20-27 kilodalton (kDa)) proteins with very similar structure. They have four transmembrane domains, with the N-terminus and the C-terminus in the cytoplasm. Claudin family member Claudin-15 is a classic tight junction molecule.
