DAPK1 Antibody 1 Publications

Rabbit Polyclonal| Catalog number: 25136-1-AP

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Freight/Packing

Con: 57 μg/150 μl

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Species specificity:
human

Positive WB detected in:
A549 cells

Positive IHC detected in:
human small intestine tissue

Positive IF detected in:
A549 cells

Recommended dilution:
WB : 1:500-1:1000
IHC : 1:100-1:400
IF : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
death-associated protein kinase 1

Calculated molecular weight:
1430aa,160 kDa

Observed molecular weight:
140-160 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
DAPK1

Synonyms
DAP kinase 1, DAPK, DAPK1, DKFZp781I035
Background

DAPK1(Death-associated protein kinase 1) is a stress-activated tumor suppressor protein that plays a role in both proapoptotic or antiapoptotic signal transduction pathways. Loss of DAPK1 expression is associated with a selective advantage fortumor cells to resist apoptotic stimuli, allowing them to separate from the original tumor; from this point of view, DAPK1 could be considered a tumor metastases inhibitor gene(PMID:17319784). This protein has 3 isoforms produced by alternative splicing.


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