DMBX1 Polyclonal antibody

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• DMBX1 Polyclonal antibody (33988-1-AP)

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  WB analysis using 33988-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 33988-1-AP (DMBX1 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours.

DMBX1 Polyclonal Antibody for WB, ELISA

Cat No. 33988-1-AP

Publications(1)

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, ELISA

Synonyms

Diencephalon/mesencephalon homeobox protein 1, MBX, Orthodenticle homolog 3, OTX3, Paired-like homeobox protein DMBX1

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Tested Applications

• Positive WB detected in: HepG2 cells, HuH-7 cells, L02 cells, SMMC-7721 cells

Recommended dilution

• Western Blot (WB): WB : 1:1000-1:6000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Published Applications

• KD/KO: See 1 publications below
• WB: See 1 publications below

Product Information

33988-1-AP targets DMBX1 in WB, ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Cited Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  CatNo: Ag41356

  Product name: Recombinant human DMBX1 protein

  Source: e coli.-derived, PGEX-4T

  Tag: GST

  Domain: 150-250 aa of BC156881

  Sequence: EGKAEAPTPDTQLDTEQPPRLPGSDPPAELHLSLSEQSASESAPEDQPDREEDPRAGAEDPKAEKSPGADSKGLGCKRGSPKADSPGSLTITPVAPGGGLL

• Full Name: diencephalon/mesencephalon homeobox 1
• Observed Molecular Weight: 41 kDa
• GenBank Accession Number: BC156881
• Gene Symbol: DMBX1
• Gene ID (NCBI): 127343
• RRID: AB_3743134
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity Purification
• UNIPROT ID: Q8NFW5
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

DMBX1 is a homeobox transcription factor with tightly regulated expression in the developing diencephalon and mesencephalon, where it governs neuronal differentiation and regional patterning. Acting through sequence-specific DNA binding, DMBX1 orchestrates developmental gene networks essential for central nervous system formation. Aberrant regulation of DMBX1 is associated with neurodevelopmental abnormalities and neural-derived cancers, underscoring its importance in neural lineage specification.

Publications

• Human
• Mouse
• Rat
• Monkey
• Pig

Species	Application	Title
human	WB	BMC Med Genomics; DMBX1 expression in colon cancer and its impact on prognosis and the tumor microenvironment.; Authors - Kaijie Zhang ; KD Validated