|Positive WB detected in||mouse testis tissue, HeLa cells, human testis tissue, rat testis tissue|
|Positive IHC detected in||mouse testis tissue|
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
|Positive IF detected in||HeLa cells|
|Western Blot (WB)||WB : 1:1000-1:6000|
|Immunohistochemistry (IHC)||IHC : 1:2000-1:8000|
|Immunofluorescence (IF)||IF : 1:20-1:200|
|Sample-dependent, check data in validation data gallery|
13714-1-AP targets DMC1 in WB, IHC, IF, ELISA applications and shows reactivity with human, mouse, rat samples.
|Tested Reactivity||human, mouse, rat|
|Cited Reactivity||human, mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||DMC1 fusion protein Ag4653|
|Full Name||DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination (yeast)|
|Calculated molecular weight||165 aa, 18 kDa, 38 kDa|
|Observed molecular weight||37 kDa|
|GenBank accession number||BC035658|
|Gene ID (NCBI)||11144|
|Purification Method||Antigen affinity purification|
|Storage Buffer||PBS with 0.02% sodium azide and 50% glycerol pH 7.3.|
|Storage Conditions||Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.|
Nucleic Acids Res
NAT10-mediated N4-acetylcytidine modification is required for meiosis entry and progression in male germ cells.
Nucleic Acids Res
MEIOK21: a new component of meiotic recombination bridges required for spermatogenesis.
ZFP541 and KCTD19 regulate chromatin organization and transcription programs for male meiotic progression
Cell Death Differ
NBS1 is required for SPO11-linked DNA double-strand break repair in male meiosis.
A missense in HSF2BP causing primary ovarian insufficiency affects meiotic recombination by its novel interactor C19ORF57/BRME1.
The Ectopic Expression of Meiosis Regulatory Genes in Cutaneous T-Cell Lymphomas (CTCL).