DNAH11 Polyclonal antibody, PBS Only

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• DNAH11 Polyclonal antibody, PBS Only (31281-1-PBS)

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  IHC staining of mouse lung using 31281-1-AP (same clone as 31281-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse lung tissue slide using 31281-1-AP (DNAH11 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 31281-1-PBS in a different storage buffer formulation.

DNAH11 Polyclonal Antibody for IHC, Indirect ELISA

Cat No. 31281-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

IHC, Indirect ELISA

Synonyms

DNHBL, Ciliary dynein heavy chain 11, CILD7

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Product Information

31281-1-PBS targets DNAH11 in IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.

• Tested Reactivity: human, mouse
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  CatNo: Ag34658

  Product name: Recombinant human DNAH11 protein

  Source: e coli.-derived, PGEX-4T

  Tag: GST

  Domain: 700-900 aa of NM_001277115

  Sequence: FNLNQPLVKFSAINGLLCVNFDPKLVAVLREVKYLLMLKKQDIPDSALAIFKKRNTILKYIGNLDLLVQGYNKLKQTLLEVEYPLIEDELRAIDEQLTAATTWLTWQDDCWGYIERVRAATSELEHRVERTQKNVKVIQQTMRGWARCVLPPRREHRREAAFTLEDKGDLFTKKYKLIQGDGCKIHNLVEENRKLFKANPS

• Full Name: dynein, axonemal, heavy chain 11
• Calculated Molecular Weight: 520 kDa
• GenBank Accession Number: NM_001277115
• Gene Symbol: DNAH11
• Gene ID (NCBI): 8701
• RRID: AB_3669928
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: Q96DT5
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

DNAH11 (dynein axonemal heavy chain 11) encodes a ciliary outer dynein arm (ODA) protein. Human DNAH11 is important for organ lateralization and likely also for the function of respiratory cilia. DNAH11 mutations are a common cause of PCD with normal ciliary ultrastructure and hyperkinetic ciliary beating (PMID: 26909801).