DRD2 Recombinant monoclonal antibody

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• DRD2 Recombinant monoclonal antibody (88509-1-RR)

DRD2 Uni-rAb^® Recombinant Antibody for WB, ELISA

Cat No. 88509-1-RR

Clone No.261031C5

Host / Isotype

Rabbit / IgG

Reactivity

human, pig

Applications

WB, ELISA

Synonyms

D(2) dopamine receptor, D2 dopamine receptor, D2DR, D2R, Dopamine D2 receptor

• 

  WB analysis using 88509-1-RR

  Various lysates were subjected to SDS PAGE followed by western blot with 88509-1-RR (DRD2 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours.

• 

  WB analysis of SH-SY5Y using 88509-1-RR

  SH-SY5Y cells were subjected to SDS PAGE followed by western blot with 88509-1-RR (DRD2 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours.

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Tested Applications

• Positive WB detected in: HEK-293 cells, SH-SY5Y cells, IM-9 cells, Fetal human brain tissue, Pig brain tissue

Recommended dilution

• Western Blot (WB): WB : 1:2000-1:10000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

88509-1-RR targets DRD2 in WB, ELISA applications and shows reactivity with human, pig samples.

• Tested Reactivity: human, pig
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen:

  Peptide

• Full Name: dopamine receptor D2
• Calculated Molecular Weight: 51 kDa
• Observed Molecular Weight: 50 kDa
• GenBank Accession Number: NM_016574
• Gene Symbol: DRD2
• Gene ID (NCBI): 1813
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: P14416
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

DRD2, also named D2DR and D2R, belongs to the G-protein coupled receptor 1 family. It is one of the five types (D1 to D5) of receptors for dopamine. The activity of DRD2 is mediated by G proteins which inhibit adenylyl cyclase. Defects in DRD2 are associated with dystonia type 11 (DYT11). The antibody is specific to DRD2.