DSCAML1 Polyclonal antibody, PBS Only

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• DSCAML1 Polyclonal antibody, PBS Only (32634-1-PBS)

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  WB analysis using 32634-1-AP (same clone as 32634-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 32634-1-AP (DSCAML1 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 32634-1-PBS in a different storage buffer formulation.

DSCAML1 Polyclonal Antibody for WB, Indirect ELISA

Cat No. 32634-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Synonyms

Cell adhesion molecule DSCAML1, Down syndrome cell adhesion molecule 2, Down syndrome cell adhesion molecule-like protein 1, DSCAM2, KIAA1132

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Product Information

32634-1-PBS targets DSCAML1 in WB, Indirect ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  CatNo: Ag36336

  Product name: Recombinant human DSCAML1 protein

  Source: e coli.-derived, PET28a

  Tag: 6*His

  Domain: 1879-2053 aa of NM_020693

  Sequence: ADRGKNVAVPIPHRANKSDYCNLPLYAKSEAFFRKADGREPCPVVPPREASIRNLARTYHTQARHLTLDPASKSLGLPHPGAPAAASTATLPQRTLAMPAPPAGTAPPAPGPTPAEPPTAPSAAPPAPSTEPPRAGGPHTKMGGSRDSLLEMSTSGVGRSQKQGAGAYSKSYTLV

• Full Name: Down syndrome cell adhesion molecule like 1
• Calculated Molecular Weight: 224 kDa
• Observed Molecular Weight: 224 kDa
• GenBank Accession Number: NM_020693
• Gene Symbol: DSCAML1
• Gene ID (NCBI): 57453
• RRID: AB_3742686
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity Purification
• UNIPROT ID: Q8TD84
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

Down syndrome cell adhesion molecule-like protein 1 (DSCAML1) is a transmembrane protein with ten immunoglobulin (Ig) and six fibronectin type III domains (PMID: 11453658). It is involved in neuronal cell adhesion and plays a crucial role in the development and function of the nervous system. DSCAML1 has been shown to participate in neuronal tiling, avoidance of neurite fasciculation, and axon guidance (PMID: 18216855; 21029858). Additionally, DSCAML1 is required for the proper placement of GABAergic neurons in the entorhinal cortex (ECx) and suppression of seizure susceptibility in rodents (PMID: 33256836).