Tested Applications
| Positive WB detected in | mouse retina tissue, rat skeletal muscle tissue |
Recommended dilution
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:500-1:1000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Published Applications
| IF | See 1 publications below |
Product Information
15568-1-AP targets DUSP26 in WB, IF, ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Reactivity | human, mouse, rat |
| Cited Reactivity | mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag7831 Product name: Recombinant human DUSP26 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-211 aa of BC001613 Sequence: MCPGNWLWASMTFMARFSRSSSRSPVRTRGTLEEMPTVQHPFLNVFELERLLYTGKTACNHADEVWPGLYLGDQDMANNRRELRRLGITHVLNASHSRWRGTPEAYEGLGIRYLGVEAHDSPAFDMSIHFQTAADFIHRALSQPGGKILVHCAVGVSRSATLVLAYLMLYHHLTLVEAIKKVKDHRGIIPNRGFLRQLLALDRRLRQGLEA Predict reactive species |
| Full Name | dual specificity phosphatase 26 (putative) |
| Calculated Molecular Weight | 24 kDa |
| Observed Molecular Weight | 20~24 kDa |
| GenBank Accession Number | BC001613 |
| Gene Symbol | DUSP26 |
| Gene ID (NCBI) | 78986 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q9BV47 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
Dual specificity phosphatase 26 (DUSP26) is an atypical DUSP with a range of physiological substrates including the MAPKs. DUSP26 is highly expressed in neuro-endocrine tissue and is absent in several human cancer cell lines including those derived from brain tumours, neuroblastomas, squamous tumours, lymphoma, colon cancer, non-small cell lung cancer, melanoma, prostatic carcinoma, breast carcinoma and cervical carcinoma (PMID: 33466673, 39222869). DUSP26 exerts a cytoprotective role by selectively dephosphorylating p53 at serine 312. DUSP26 is a 24kda atypical type Ⅰ cysteine-based dual-specificity phosphatase (PMID: 41748589, 35313355).
Protocols
| Product Specific Protocols | |
|---|---|
| WB protocol for DUSP26 antibody 15568-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
