DeltaN p63 Polyclonal antibody

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• DeltaN p63 Polyclonal antibody (33460-1-AP)

DeltaN p63 Polyclonal Antibody for IHC, ELISA

Cat No. 33460-1-AP

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

IHC, ELISA

Synonyms

p63, TP63, CUSP, TP 63, Transformation-related protein 63

• 

  IHC staining of human cervical cancer using 33460-1-AP

  Immunohistochemical analysis of paraffin-embedded human cervical cancer tissue slide using 33460-1-AP (DeltaN p63 antibody) at dilution of 1:2000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

  This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy
• 

  IHC staining of human cervical cancer using 33460-1-AP

  Immunohistochemical analysis of paraffin-embedded human cervical cancer tissue slide using 33460-1-AP (DeltaN p63 antibody) at dilution of 1:2000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

  This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy

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Tested Applications

• Positive IHC detected in: human cervical cancer tissue; Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

• Immunohistochemistry (IHC): IHC : 1:1000-1:4000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

33460-1-AP targets DeltaN p63 in IHC, ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  Peptide

• Full Name: tumor protein p63
• Calculated Molecular Weight: 66 kDa
• GenBank Accession Number: NM_001114980
• Gene Symbol: TP63
• Gene ID (NCBI): 8626
• RRID: AB_3742981
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity Purification
• UNIPROT ID: Q9H3D4-2
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

DeltaNp63 (ΔNp63), often referred to as p40, is a key isoform of the TP63 gene, which belongs to the p53 tumor suppressor family. Unlike the full-length TAp63 isoform, ΔNp63 lacks the N-terminal transactivation domain (TAD) and functions primarily as a dominant-negative inhibitor of p53, TAp63, and TAp73.