EIF2C4 Polyclonal antibody

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EIF2C4 Polyclonal Antibody for ELISA

Cat No. 19693-1-AP

Publications(1)

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, ELISA

Synonyms

AGO4, Argonaute4, eIF 2C 4, eIF2C 4, EIF2C4, hAgo4, KIAA1567, Protein argonaute 4

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Published Applications

• WB: See 1 publications below

Product Information

19693-1-AP targets EIF2C4 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Cited Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: Peptide
• Full Name: eukaryotic translation initiation factor 2C, 4
• Calculated Molecular Weight: 97 kDa
• GenBank Accession Number: NM_017629
• Gene Symbol: EIF2C4
• Gene ID (NCBI): 192670
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: Q9HCK5
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

EIF2C4, also named as AGO4 and KIAA1567, belongs to the argonaute family and Ago subfamily. It is required for RNA-mediated gene silencing (RNAi). EIF2C4 binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. EIF2C4 lacks endonuclease activity and does not appear to cleave target mRNAs. It is also required for RNA-directed transcription and replication of the human hapatitis delta virus (HDV).

Publications

Species	Application	Title
human	WB	J Biol Chem; Pannexin 1 mediates ferroptosis that contributes to renal ischemia/reperfusion injury.; Authors - Lianjiu Su