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  • KD/KO Validated

ETV5 Polyclonal antibody

ETV5 Polyclonal Antibody for IF, WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IF, Chip, ELISA

Conjugate

Unconjugated

Cat no : 13011-1-AP

Synonyms

ERM, Ets related protein ERM, ETS translocation variant 5, ets variant 5, ETV5



Tested Applications

Positive WB detected inPC-3 cells
Positive IF detected inPC-3 cells

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:500-1:2000
Immunofluorescence (IF)IF : 1:50-1:500
Sample-dependent, check data in validation data gallery

Product Information

13011-1-AP targets ETV5 in WB, IF, Chip, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivity human, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen ETV5 fusion protein Ag3708
Full Name ets variant 5
Calculated molecular weight 510 aa, 58 kDa
Observed molecular weight 58 kDa
GenBank accession numberBC007333
Gene symbol ETV5
Gene ID (NCBI) 2119
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

ETS variant gene 5(ETV5) belongs to the ETS oncogene family that shares a conserved peptide, ETS domain, which mediates sequence-specific DNA binding. ETV5 is a transcription factor and is required for spermatogonial stem cell self-renewal. ETV5 can be negatively regulated by COP1, a tumor suppressor. Also it has a role in branching morphogenesis in the developing kidney

Protocols

Product Specific Protocols
WB protocol for ETV5 antibody 13011-1-APDownload protocol
IF protocol for ETV5 antibody 13011-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
mouseWB

Mol Cell Endocrinol

ETV5 regulates GOAT/ghrelin system in an mTORC1-dependent manner.

Authors - Zhuo Mao
  • KD Validated
mouseIF

Dev Cell

FAT4 Fine-Tunes Kidney Development by Regulating RET Signaling.

Authors - Hongtao Zhang
mouseWB,IF

Nat Commun

Capicua regulates neural stem cell proliferation and lineage specification through control of Ets factors.

Authors - Shiekh Tanveer Ahmad
mouse

BMC Biol

Biological and RNA regulatory function of MOV10 in mammalian germ cells.

Authors - Kaiqiang Fu

Endocr Relat Cancer

Interaction of BRAF-induced ETS factors with mutant TERT promoter in papillary thyroid cancer.

Authors - Young Shin Song
humanWB

J Biol Chem

ETS variant transcription factor 5 and c-Myc cooperate in derepressing the human telomerase gene promoter via composite Ets/E-box motifs.

Authors - Fan Zhang
  • KD Validated