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  • KD/KO Validated

SEC6 Polyclonal antibody

SEC6 Polyclonal Antibody for IF, IHC, WB, ELISA

Host / Isotype

Rabbit / IgG


human, mouse, rat





Cat no : 14703-1-AP


EXOC3, exocyst complex component 3, Exocyst complex component Sec6, SEC6, SEC6L1, Sec6p

Tested Applications

Positive WB detected inhuman brain tissue, COLO 320 cells, HeLa cells, HepG2 cells
Positive IHC detected inhuman gliomas tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Positive IF detected inHepG2 cells

Recommended dilution

Western Blot (WB)WB : 1:500-1:2400
Immunohistochemistry (IHC)IHC : 1:50-1:500
Immunofluorescence (IF)IF : 1:20-1:200
Sample-dependent, check data in validation data gallery

Product Information

14703-1-AP targets SEC6 in WB, IHC, IF, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivityhuman, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen SEC6 fusion protein Ag6383
Full Name exocyst complex component 3
Calculated molecular weight 87 kDa
Observed molecular weight 86 kDa
GenBank accession numberBC064569
Gene symbol EXOC3
Gene ID (NCBI) 11336
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Exoc3 (Sec6) is a component of the exocyst (Sec6/8) complex involved in vesicle trafficking at neural synapses and vesicle targeting in polarized epithelial cells. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. This complex is composed of eight proteins (Sec3, Sec5, Sec6, Sec8, Sec10, and Sec15, Exo70 and Exo84), with molecular weights ranging from 70 to 144 kDa.


Product Specific Protocols
WB protocol for SEC6 antibody 14703-1-APDownload protocol
IHC protocol for SEC6 antibody 14703-1-APDownload protocol
IF protocol for SEC6 antibody 14703-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols



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