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FGFBP1 Polyclonal antibody

FGFBP1 Polyclonal Antibody for IHC,ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, IHC,ELISA

Conjugate

Unconjugated

Cat no : 25006-1-AP

Synonyms

17 kDa HBGF binding protein, FGF binding protein 1, FGF BP, FGF BP1, FGFBP, FGFBP 1, FGFBP1, HBP17, Heparin-binding protein 17



Tested Applications

Positive IHC detected inhuman colon cancer tissue, human breast cancer tissue, human lung cancer tissue, human skin cancer tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

ApplicationDilution
Immunohistochemistry (IHC)IHC : 1:20-1:200
Sample-dependent, check data in validation data gallery

Product Information

The immunogen of 25006-1-AP is FGFBP1 Fusion Protein expressed in E. coli.

Tested Reactivity human, mouse
Cited Reactivity mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen FGFBP1 fusion protein Ag6357
Full Name fibroblast growth factor binding protein 1
Calculated molecular weight 26 kDa
GenBank accession numberBC003628
Gene symbol FGFBP1
Gene ID (NCBI) 9982
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

FGFBP1, also named as HBP17, is prominent for its role as the chaperone for fibroblast growth factor-2 (FGF-2), which plays a crucial role in angiogenesis as well as promoting tumor growth. HBp17/FGFBP-1 has been proposed as a candidate biomarker for a number of cancers since it is frequently found to be elevated in many cancer types including in the tissue and cell lines of oral squamous cell carcinomas (OSCC).

Protocols

Product Specific Protocols
IHC protocol for FGFBP1 antibody 25006-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
mouseWB,IHC

Am J Cancer Res

Type-2 11β-hydroxysteroid dehydrogenase promotes the metastasis of colorectal cancer via the Fgfbp1-AKT pathway.

Authors - Jin Chen
  • KD Validated