FGFR1 Polyclonal antibody, PBS Only

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• FGFR1 Polyclonal antibody, PBS Only (30358-1-PBS)

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  IP experiment of SH-SY5Y using 30358-1-AP (same clone as 30358-1-PBS)

  IP result of anti-FGFR1 (IP:30358-1-AP, 4ug; Detection:30358-1-AP 1:300) with SH-SY5Y cells lysate 770 ug. This data was developed using the same antibody clone with 30358-1-PBS in a different storage buffer formulation.

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  IHC staining of human colon using 30358-1-AP (same clone as 30358-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human colon tissue slide using 30358-1-AP (FGFR1 antibody) at dilution of 1:200 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 30358-1-PBS in a different storage buffer formulation.

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  IHC staining of human colon using 30358-1-AP (same clone as 30358-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human colon tissue slide using 30358-1-AP (FGFR1 antibody) at dilution of 1:200 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 30358-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse brain using 30358-1-AP (same clone as 30358-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 30358-1-AP (FGFR1 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 30358-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse brain using 30358-1-AP (same clone as 30358-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 30358-1-AP (FGFR1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 30358-1-PBS in a different storage buffer formulation.

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  IHC staining of rat kidney using 30358-1-AP (same clone as 30358-1-PBS)

  Immunohistochemical analysis of paraffin-embedded rat kidney tissue slide using 30358-1-AP (FGFR1 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 30358-1-PBS in a different storage buffer formulation.

• 

  IHC staining of rat kidney using 30358-1-AP (same clone as 30358-1-PBS)

  Immunohistochemical analysis of paraffin-embedded rat kidney tissue slide using 30358-1-AP (FGFR1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 30358-1-PBS in a different storage buffer formulation.

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  IF Staining of SH-SY5Y using 30358-1-AP (same clone as 30358-1-PBS)

  Immunofluorescent analysis of (-20°C Ethanol) fixed SH-SY5Y cells using FGFR1 antibody (30358-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 30358-1-PBS in a different storage buffer formulation.

FGFR1 Polyclonal Antibody for IHC, IF/ICC, IP, Indirect ELISA

Cat No. 30358-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

IHC, IF/ICC, IP, Indirect ELISA

Synonyms

bFGF R 1, BFGFR, bFGF-R-1, CD331, CEK

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Product Information

30358-1-PBS targets FGFR1 in IHC, IF/ICC, IP, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  Peptide

• Full Name: fibroblast growth factor receptor 1
• Calculated Molecular Weight: 820 aa, 91 kDa
• Observed Molecular Weight: 80 kDa, 95 kDa, 105 kDa
• GenBank Accession Number: BC018128
• Gene Symbol: FGFR1
• Gene ID (NCBI): 2260
• RRID: AB_3669716
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: P11362
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

Fibroblast growth factor receptor 1 (FGFR1) is a tyrosine-protein kinase that acts as a cell-surface receptor for fibroblast growth factors. FGFR1 has been implicated in diverse biological processes including embryonic development, cell proliferation, differentiation, migration, and tumorigenesis. Mutations in the FGFR1 gene have been associated with Pfeiffer syndrome, Jackson-Weiss syndrome, Antley-Bixler syndrome, osteoglophonic dysplasia, squamous cell lung cancer, and autosomal dominant Kallmann syndrome. Alternatively spliced variants that encode different protein isoforms have been described.