FHIT Polyclonal antibody

FHIT Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG







Cat no : 13362-1-AP


AP3A hydrolase, AP3Aase, Bis(5 adenosyl) triphosphatase, Dinucleosidetriphosphatase, FHIT, FRA3B, fragile histidine triad gene

Tested Applications

Positive WB detected inHCT 116 cells, HEK-293 cells, HL-60 cells

Recommended dilution

Western Blot (WB)WB : 1:500-1:1000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

13362-1-AP targets FHIT in WB, ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen FHIT fusion protein Ag4181
Full Name fragile histidine triad gene
Calculated Molecular Weight 147 aa, 17 kDa
Observed Molecular Weight17 kDa
GenBank Accession NumberBC032336
Gene Symbol FHIT
Gene ID (NCBI) 2272
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

The candidate tumor suppressor gene, FHIT(Fragile histidine triad protein), encompasses the common human chromosomal fragile site at 3p14.2, the hereditary renal cancer translocation breakpoint, and cancer cell homozygous deletions. Fhit hydrolyzes dinucleotide 5',5'''-P1,P3-triphosphate in vitro and mutation of a central histidine abolishes hydrolase activity(PMID:9391102). FHIT has a major role in regulating beta-catenin-mediated gene transcription.


Product Specific Protocols
WB protocol for FHIT antibody 13362-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols