Product Information
24845-1-PBS targets FIGLA in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Reactivity | human, mouse, rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag20392 Product name: Recombinant human FIGLA protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-219 aa of BC148798 Sequence: MDPAPGVLDPRAAPPALLGTPQAEVLEDVLREQFGPLPQLAAVCRLKRLPSGGYSSTENLQLVLERRRVANAKERERIKNLNRGFARLKALVPFLPQSRKPSKVDILKGATEYIQVLSDLLEGAKDSKKQDPDEQSYSNNSSESHTSSARQLSRNITQHISCAFGLKNEEEGPWADGGSGEPAHACRHSVMSTTEIISPTRSLDRFPEVELLSHRLPQV Predict reactive species |
| Full Name | folliculogenesis specific basic helix-loop-helix |
| Calculated Molecular Weight | 219 aa, 24 kDa |
| Observed Molecular Weight | 20 kDa |
| GenBank Accession Number | BC148798 |
| Gene Symbol | FIGLA |
| Gene ID (NCBI) | 344018 |
| RRID | AB_3742126 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q6QHK4 |
| Storage Buffer | PBS only, pH 7.3. |
| Storage Conditions | Store at -80°C. |
Background Information
Folliculogenesis specific bHLH transcription factor(FIGLA) also known as POF6, is an oocyte-specific transcription factor expressed mainly in ovarian follicles and involved in regulating follicle formation and oocyte development. It regulates the expression of oocyte zona pellucida genes (such as Zp1, Zp2 and Zp3) by binding to the promoter regions of these genes (PMID: 15044608). Mutations in this gene cause premature ovarian failure type 6(PMID: 18499083).
