FIGNL1 Recombinant monoclonal antibody, PBS Only

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• FIGNL1 Recombinant monoclonal antibody, PBS Only (86971-2-PBS)

FIGNL1 Uni-rAb^® Recombinant Antibody for WB, IF/ICC, Indirect ELISA

Cat No. 86971-2-PBS

Clone No.252109G9

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, IF/ICC, Indirect ELISA

Synonyms

EC:3.6.4.-, Fidgetin-like protein 1

• 

  WB analysis using 86971-2-RR (same clone as 86971-2-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 86971-2-RR (FIGNL1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86971-2-PBS in a different storage buffer formulation.

  This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy
• 

  IF Staining of U2OS using 86971-2-RR (same clone as 86971-2-PBS)

  Immunofluorescent analysis of (4% PFA) fixed U2OS cells using FIGNL1 antibody (86971-2-RR, Clone: 252109G9 ) at dilution of 1:500 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2), CL594-Phalloidin (red). This data was developed using the same antibody clone with 86971-2-PBS in a different storage buffer formulation.

  This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy
• 

  Affinity and Kinetic Characterization of 86971-2-RR

  Biolayer interferometry (BLl) kinetic assays of 86971-2-RR against Human FIGNL1 were performed. The affinity constant is 0.147 nM.

  This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy

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Product Information

86971-2-PBS targets FIGNL1 in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen:

  CatNo: Ag11709

  Product name: Recombinant human FIGNL1 protein

  Source: e coli.-derived, PGEX-4T

  Tag: GST

  Domain: 326-674 aa of BC051867

  Sequence: KSLGASRSRGILGKFVPPIPKQDGGEQNGGMQCKPYGAGPTEPAHPVDERLKNLEPKMIELIMNEIMDHGPPVNWEDIAGVEFAKATIKEIVVWPMLRPDIFTGLRGPPKGILLFGPPGTGKTLIGKCIASQSGATFFSISASSLTSKWVGEGEKMVRALFAVARCQQPAVIFIDEIDSLLSQRGDGEHESSRRIKTEFLVQLDGATTSSEDRILVVGATNRPQEIDEAARRRLVKRLYIPLPEASARKQIVINLMSKEQCCLSEEEIEQIVQQSDAFSGADMTQLCREASLGPIRSLQTADIATITPDQVRPIAYIDFENAFRTVRPSVSPKDLELYENWNKTFGCGK

• Full Name: fidgetin-like 1
• Calculated Molecular Weight: 674 aa, 74 kDa
• Observed Molecular Weight: 70 kDa
• GenBank Accession Number: BC051867
• Gene Symbol: FIGNL1
• Gene ID (NCBI): 63979
• RRID: AB_3745243
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: Q6PIW4
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

Fidgetin-like 1 (FIGNL1), a subfamily member of ATPases, is associated with diverse cellular activities (AAA proteins). FIGNL1 is involved in DNA repair.FIGNL1 plays a crucial role in the occurrence and development of malignant tumors. FIGNL1 participates in the prognosis, promoter methylation, and immune infiltrates in KIRP, LGG, and LIHC (PMID: 35232348).