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Tested Applications
| Positive WB detected in | mouse brain tissue |
Recommended dilution
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:500-1:1000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Product Information
55055-1-AP targets Toca 1 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Reactivity | human, mouse, rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
Peptide Predict reactive species |
| Full Name | formin binding protein 1-like |
| Calculated Molecular Weight | 70 kDa |
| Observed Molecular Weight | 63-75 kDa |
| GenBank Accession Number | NM_017737 |
| Gene Symbol | Toca 1 |
| Gene ID (NCBI) | 54874 |
| RRID | AB_10858792 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q5T0N5 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
Toca-1, also named as FNBP1L or C1orf39, belongs to the FNBP1 family. It is required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. Toca-1 may bind to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promote membrane invagination and the formation of tubules. Also promotes CDC42-induced actin polymerization by activating the WASL/N-WASP-WASPIP/WIP complex, the predominant form of WASL/N-WASP in cells. The antibody is specific to Toca-1.
Protocols
| Product Specific Protocols | |
|---|---|
| WB protocol for Toca 1 antibody 55055-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
