FOXD2 Polyclonal antibody

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• FOXD2 Polyclonal antibody (34275-1-AP)

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  WB analysis using 34275-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 34275-1-AP (FOXD2 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours.

FOXD2 Polyclonal Antibody for WB, ELISA

Cat No. 34275-1-AP

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, ELISA

Synonyms

FKHL17, Forkhead box protein D2, Forkhead-related protein FKHL17, Forkhead-related transcription factor 9, FREAC9

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Tested Applications

• Positive WB detected in: BGC-823 cells, HGC-27 cells, SGC-7901 cells

Recommended dilution

• Western Blot (WB): WB : 1:500-1:1000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

34275-1-AP targets FOXD2 in WB, ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  CatNo: Ag41978

  Product name: Recombinant human FOXD2 protein

  Source: e coli.-derived, PGEX-4T

  Tag: GST

  Domain: 11-100 aa of NM_004474.4

  Sequence: MSSESSPAALSEADADIDVVGGGSGGGELPARSGPRAPRDVLPHGHEPPAEEAEADLAEDEEESGGCSDGEPRALASRGAAAAAGSPGPG

• Full Name: forkhead box D2
• Calculated Molecular Weight: 49kDa，495aa
• Observed Molecular Weight: 51 kDa
• GenBank Accession Number: NM_004474.4
• Gene Symbol: FOXD2
• Gene ID (NCBI): 2306
• RRID: AB_3743182
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity Purification
• UNIPROT ID: O60548
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

FOXD2, as one descendant of the FOX gene family, has been mentioned in many articles to show a high expression in several cancers. FOXD2 showed a high expression in gastric adenocarcinoma tissues and cells, and silencing FOXD2 could hinder gastric adenocarcinoma cell proliferation. In addition, FOXD2 could facilitate gastric adenocarcinoma cell proliferation by activating the expression of its downstream gene IQGAP3 and increasing intracellular Ca2+ concentration (PMID: 37724892).