|Positive WB detected in||mouse ovary tissue|
|Western Blot (WB)||WB : 1:500-1:2000|
|Sample-dependent, check data in validation data gallery|
19672-1-AP targets FOXL2-Specific in WB, IHC, IF, ELISA applications and shows reactivity with human, mouse, rat samples.
|Tested Reactivity||human, mouse, rat|
|Cited Reactivity||chicken, human|
|Host / Isotype||Rabbit / IgG|
|Full Name||forkhead box L2|
|Calculated molecular weight||39 kDa|
|Observed molecular weight||49 kDa|
|GenBank accession number||NM_023067|
|Gene ID (NCBI)||668|
|Purification Method||Antigen affinity purification|
|Storage Buffer||PBS with 0.02% sodium azide and 50% glycerol pH 7.3.|
|Storage Conditions||Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.|
FOXL2 is probable a transcriptional regulator. It is required to maintain the female phenotype throughout adulthood, and may provide clues to female infertility. Defects in FOXL2 are a cause of blepharophimosis, ptosis, and epicanthus inversus syndrome (BPES) Defects in FOXL2 are a cause of premature ovarian failure type 3 (POF3). This antibody is specific to the C-term of FOXL2.
Aging (Albany NY)
Coherent apoptotic and autophagic activities involved in regression of chicken postovulatory follicles.
Clin Cancer Res
HMGA2-FOXL2 Axis Regulates Metastases and Epithelial-to-mesenchymal Transition of Chemo-resistant Gastric Cancer.
The reviews below have been submitted by verified Proteintech customers who received an incentive forproviding their feedback.
Y C (Verified Customer) (01-23-2020)
I use the free trial size antibody code from the 12 days of free X'mas gifts to order this. Free product and one figure!! Yay!
Kathryn (Verified Customer) (11-04-2019)
Image shows post-natal day 2 mouse ovary with germ cells marked by TRA98 (Abcam) in green and granulosa cells marked by FOXL2 (Proteintech) in red. This is an excellent granulosa cell marker.