Product Information
84144-1-PBS targets FOXL2-Specific in WB, ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Reactivity | human, mouse, rat |
| Host / Isotype | Rabbit / IgG |
| Class | Recombinant |
| Type | Antibody |
| Immunogen |
Peptide Predict reactive species |
| Full Name | forkhead box L2 |
| Calculated Molecular Weight | 39 kDa |
| Observed Molecular Weight | 45-50 kDa |
| GenBank Accession Number | NM_023067 |
| Gene Symbol | FOXL2 |
| Gene ID (NCBI) | 668 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purfication |
| UNIPROT ID | P58012 |
| Storage Buffer | PBS only, pH 7.3. |
| Storage Conditions | Store at -80°C. |
Background Information
FOXL2 is a critical factor essential for ovary differentiation and maintenance, and repression of the genetic program for somatic testis determination. It prevents trans-differentiation of ovary to testis through transcriptional repression of the sertoli cell-promoting gene SOX9. FOXL2 is mainly expressed in ovary, parathyroid gland and sex cord-stromal tumors.

