FRMD1 Polyclonal antibody

• 

  WB analysis using 31908-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 31908-1-AP (FRMD1 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours.

• 

  WB analysis of K-562 using 31908-1-AP

  WB result of FRMD1 antibody (31908-1-AP; 1:1000; incubated at room temperature for 1.5 hours) with sh-Control and sh-FRMD1 transfected K-562 cells.

• Featured Product
• KD/KO Validated

FRMD1 Polyclonal Antibody for WB, ELISA

Cat No. 31908-1-AP

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, ELISA

Synonyms

FERM domain-containing protein 1

---

Tested Applications

• Positive WB detected in: mouse colon tissue, K-562 cells, mouse testis tissue, mouse thymus tissue, rat thymus tissue

Recommended dilution

• Western Blot (WB): WB : 1:1000-1:4000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

31908-1-AP targets FRMD1 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: FRMD1 fusion protein Ag36382
• Full Name: FERM domain containing 1
• Observed Molecular Weight: 70 kDa
• GenBank Accession Number: BC137144
• Gene Symbol: FRMD1
• Gene ID (NCBI): 79981
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity Purification
• UNIPROT ID: Q8N878
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

The FERM structural domain of FRMD1 (FERM Domain Containing 1) is widely found in cytoskeleton-associated proteins, which are capable of connecting the cytoskeleton to the cell membrane and is involved in signaling. FRMD1 is predicted to be involved in the positive regulation of the Hippo signaling pathway and may play a role in the cytoplasmic side of the cytoskeleton and apical plasma membrane. Although there are fewer studies on the role of FRMD1 in disease, its expression pattern in cancer and lymphoid tissues suggests that it may have important biological functions.