Product Information
24560-1-PBS targets FYTTD1 in WB, Indirect ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag20051 Product name: Recombinant human FYTTD1 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 68-128 aa of BC039734 Sequence: MRVRWGIQQNSGFGKTSLNRRGRVMPGKRRPNGVITGLAARKTTGIRKGISPMNRPPLSDK Predict reactive species |
| Full Name | forty-two-three domain containing 1 |
| Calculated Molecular Weight | 318 aa, 36 kDa |
| Observed Molecular Weight | 50 kDa |
| GenBank Accession Number | BC039734 |
| Gene Symbol | FYTTD1 |
| Gene ID (NCBI) | 84248 |
| RRID | AB_2879609 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q96QD9 |
| Storage Buffer | PBS only, pH 7.3. |
| Storage Conditions | Store at -80°C. |
Background Information
FYTTD1, also termed as UAP56 interacting factor or UIF, is a 318 amino acid protein, that belongs to the UIF family. FYTTD1 localizes to the nucleus and is required for mRNA export from the nucleus to the cytoplasm. Functioning as an adaptor, FYTTD1 utilizes the BAT1/DDX39-TAP pathway, which is essential for efficient mRNA export and nuclear pore delivery. FYTTD1 interacts with SSRP1, a protein that is necessary for its recruitment of mRNAs, in addition to a mutually exclusive interaction with BAT1/DDX39 and TAP. The molecular weight of post-translational modified FYTTD1 is observed to be 50 kDa.
