Fabp4 Polyclonal antibody

Fabp4 Polyclonal Antibody for ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat and More (1)

Applications

WB, IF, ELISA

Conjugate

Unconjugated

Publications

2

Cat no : 51035-1-AP

Synonyms

422/aP2, ALBP/Ap2, Ap2, Fabp4, Lbpl

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Validation Data Gallery

• 

  WB analysis of mouse skin using 51035-1-AP

  mouse skin tissue were subjected to SDS PAGE followed by western blot with 51035-1-AP (Fabp4 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

• 

  WB analysis of mouse small intestine using 51035-1-AP

  mouse small intestine tissue were subjected to SDS PAGE followed by western blot with 51035-1-AP (Fabp4 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

• 

  WB analysis of mouse heart using 51035-1-AP

  mouse heart tissue were subjected to SDS PAGE followed by western blot with 51035-1-AP (Fabp4 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

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Published Applications

• WB: See 1 publications below
• IF: See 1 publications below

Product Information

51035-1-AP targets Fabp4 in WB, IF, ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Cited Reactivity: mouse, pig
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: Fabp4 fusion protein Ag0712
• Full Name: fatty acid binding protein 4, adipocyte
• Calculated Molecular Weight: 15 kDa
• Observed Molecular Weight: 15 kDa
• GenBank Accession Number: BC054426
• Gene Symbol: Fabp4
• Gene ID (NCBI): 11770
• RRID: AB_670380
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
• Storage Conditions: Store at -20°C. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Fatty acid binding protein (FABP) 4 is a member of the FABP family which abundantly expressed, fatty acid carrier proteins. FABPs are capable of binding a variety of hydrophobic molecules such as long-chain fatty acids and are important for their uptake and intracellular trafficking. It was first identified as an adipocyte-specific protein, important for the maintenance of lipid and glucose metabolism. It is also detected in macrophages, where it participates in regulating inflammation and cholesterol trafficking via NFκB and PPAR. In more recent studies, FABP4 has been found in a variety of endothelial cells, where it has been identified as a target of VEGF and a regulator of cell proliferation and possibly angiogenesis. Pathologically, FABP4 has been associated with the development of metabolic syndrome, diabetes and cancer and vulnerability of atherosclerotic plaques. FABP4 has been identified as a novel prognostic factor for both adverse cardiovascular events and breast cancer.

Publications

Species	Application	Title
mouse	IF	Cell; Ciliary Hedgehog Signaling Restricts Injury-Induced Adipogenesis.; Authors - Daniel Kopinke
pig	WB	J Anim Sci; Antimicrobial peptide KR-32 alleviates Escherichia coli K88-induced fatty acid malabsorption by improving expression of FATP4.; Authors - H Liu