Factor XIIIb Polyclonal antibody

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Factor XIIIb Polyclonal Antibody for WB, ELISA

Cat No. 20269-1-AP Copied!

Publications (1)

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Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, ELISA

Synonyms

F13B, Fibrin-stabilizing factor B subunit, FXIIIB, FXIII-B, Protein-glutamine gamma-glutamyltransferase B chain

• 

  WB analysis of human plasma using 20269-1-AP

  human plasma were subjected to SDS PAGE followed by western blot with 20269-1-AP (Factor XIIIb antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours.

  This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy

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Tested Applications

• Positive WB detected in: human plasma

Recommended dilution

• Western Blot (WB): WB : 1:500-1:3000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

20269-1-AP targets Factor XIIIb in WB, ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Cited Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  Peptide

• Full Name: coagulation factor XIII, B polypeptide
• Calculated Molecular Weight: 76 kDa
• Observed Molecular Weight: ~80 kDa
• GenBank Accession Number: NM_001994
• Gene Symbol: Factor XIIIb
• Gene ID (NCBI): 2165
• RRID: AB_3085601
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: P05160
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Coagulation factor XIII (FXIII) is a blood proenzyme that catalyzes intermolecular cross-linking of fibrinogen and is involved in the clotting cascade. Factor XIII is composed of two catalytic FXIIIa and two protective/regulatory FXIIIb subunits. FXIIIb is the carrier/regulatory protein of its partner FXIIIa subunit. (PMID: 36372609; PMID: 1359667)

Publications

What published studies show

The Factor XIIIb Polyclonal antibody (Cat# 20269-1-AP) has 1 citation to date. It was cited in Biomol Biomed (Impact Factor 2.8) in a 2024 study investigating F13B's role in regulating angiogenesis and tumor progression in hepatocellular carcinoma via the HIF-1α/VEGF pathway. The research field encompasses liver cancer biology, angiogenesis, and hypoxia signaling.

Automatically generated from the 1 publication citations by Able AI.

• Human
• Mouse
• Rat
• Monkey
• Pig

Species	Application	Title
human	WB	Biomol Biomed; F13B regulates angiogenesis and tumor progression in hepatocellular carcinoma via the HIF-1α/VEGF pathway; Authors - Dong Jiang ; KO Validated