Filter:
Product Information
98430-1-PBS targets Fas Ligand/CD178 in FC applications and shows reactivity with rat samples.
| Tested Reactivity | rat |
| Host / Isotype | Rabbit / IgG |
| Class | Recombinant |
| Type | Antibody |
| Immunogen | Fas Ligand/CD178 fusion protein Eg3218 Predict reactive species |
| Full Name | Fas ligand (TNF superfamily, member 6) |
| Calculated Molecular Weight | 31 kDa |
| GenBank Accession Number | NM_012908.1 |
| Gene Symbol | Faslg |
| Gene ID (NCBI) | 25385 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purification |
| UNIPROT ID | P36940 |
| Storage Buffer | PBS only, pH 7.3. |
| Storage Conditions | Store at -80°C. |
Background Information
CD178, also known as Fas ligand, is a type II transmembrane protein that belongs to the tumor necrosis factor (TNF) family. It is expressed on NK cells, cytotoxic T lymphocytes and activated CD4+ Th1 cells. CD178 transduces apoptotic signal into cells by binding to FAS/CD95. It is involved as a death factor in the regulation of activation-induced cell death, establishment of immune privilege and tumor cell survival.
