GABRR1 Polyclonal antibody

GABRR1 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, IF, ELISA

Conjugate

Unconjugated

Cat no : 25899-1-AP

Synonyms

GABA(A) receptor subunit rho 1, GABA(C) receptor, GABRR1



Tested Applications

Positive WB detected inmouse brain tissue, mouse skeletal muscle tissue

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:500-1:1000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

The immunogen of 25899-1-AP is GABRR1 Fusion Protein expressed in E. coli.

Tested Reactivity human, mouse
Cited Reactivitymouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen GABRR1 fusion protein Ag23165
Full Name gamma-aminobutyric acid (GABA) receptor, rho 1
Calculated Molecular Weight 479 aa, 56 kDa
Observed Molecular Weight 50-56 kDa
GenBank Accession NumberBC130344
Gene Symbol GABRR1
Gene ID (NCBI) 2569
RRIDAB_2880290
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

GABRR1 is a member of a family of ligand-gated chloride channels that are the major inhibitory neurotransmitter receptors in the central nervous system. GABRR1 acts as a rho-1 receptor of GABA, the major inhibitory neurotransmitter in the vertebrate brain, may play a role in retinal neurotransmission. And then, GABRR1 is highly expressed in the retina and in a lesser extent in brain, lung and thymus. There are 3 isoforms for GABRR1 produced by alternative splicing, with the molecular weights of 46 kDa, 53 kDa, 56 kDa, respectively.

Protocols

Product Specific Protocols
WB protocol for GABRR1 antibody 25899-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
IF

Insect Sci

Rho 1 participates in parasitoid wasp eggs maturation and host cellular immunity inhibition

Authors - Ruijuan Wang
mouseWB

Transl Psychiatry

Acute stress induces severe neural inflammation and overactivation of glucocorticoid signaling in interleukin-18-deficient mice

Authors - Kyosuke Yamanishi