Product Information
10277-1-AP targets GADD45G in WB, ELISA applications and shows reactivity with human, mouse samples.
| Tested Reactivity | human, mouse |
| Cited Reactivity | mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag0273 Product name: Recombinant human GADD45G protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-127 aa of BC000465 Sequence: MTLEEVRGQDTVPESTARMQGAGKALHELLLSAQRQGCLTAGVYESAKVLNVDPDNVTFCVLAAGEEDEGDIALQIHFTLIQAFCCENDIDIVRVGDVQRLAAIVGAGEEAGAPGDLHCILISNPNE Predict reactive species |
| Full Name | growth arrest and DNA-damage-inducible, gamma |
| Calculated Molecular Weight | 17 kDa |
| GenBank Accession Number | BC000465 |
| Gene Symbol | GADD45G |
| Gene ID (NCBI) | 10912 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | O95257 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
GADD45G, also named as CR6, DDIT2 and GRP17, is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. GADD45G responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The GADD45G is highly expressed in placenta.
Publications
What published studies show
The GADD45G Polyclonal antibody (Cat# 10277-1-AP) has 1 total citation. It appears in Experimental Molecular Pathology (2007), where it was used for Western blot in a mouse study investigating Mallory body formation and epigenetic phenotypic changes in hepatocytes. The associated research field is liver pathology and epigenetics.
| Species | Application | Title |
|---|---|---|
Exp Mol Pathol Mallory body formation is associated with epigenetic phenotypic change in hepatocytes in vivo. |
