• Featured Product
  • KD/KO Validated

GAS1 Polyclonal antibody

GAS1 Polyclonal Antibody for IHC, WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, IHC, IF, ELISA

Conjugate

Unconjugated

Cat no : 17903-1-AP

Synonyms

GAS 1, GAS1, growth arrest 1



Tested Applications

Positive WB detected inmouse brain tissue
Positive IHC detected inhuman gliomas tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:500-1:2000
Immunohistochemistry (IHC)IHC : 1:50-1:500
Sample-dependent, check data in validation data gallery

Product Information

The immunogen of 17903-1-AP is GAS1 Fusion Protein expressed in E. coli.

Tested Reactivity human, mouse
Cited Reactivityhuman, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen GAS1 fusion protein Ag12275
Full Name growth arrest-specific 1
Calculated molecular weight 345 aa, 36 kDa
Observed molecular weight 36 kDa
GenBank accession numberBC074908
Gene symbol GAS1
Gene ID (NCBI) 2619
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

GAS1 is involved in growth suppression. It is an integral plasma membrane protein whose expression is linked to growth arrest. It can be used as a novel therapeutic candidate for gastric cancer.

Protocols

Product Specific Protocols
WB protocol for GAS1 antibody 17903-1-APDownload protocol
IHC protocol for GAS1 antibody 17903-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
human,mouseWB,IF

Cancer Commun (Lond)

Bifidobacterium adolescentis orchestrates CD143+ cancer-associated fibroblasts to suppress colorectal tumorigenesis by Wnt signaling-regulated GAS1

Authors - Shujie Chen
humanIHC

Sci Rep

Gene-Related Response of Basal Cell Carcinoma to Biologic Treatment with Vismodegib.

Authors - Amir Sternfeld
humanWB,IF

Exp Ther Med

microRNA-mediated GAS1 downregulation promotes the proliferation of synovial fibroblasts by PI3K-Akt signaling in osteoarthritis.

Authors - Chuan Dong
  • KD Validated
humanWB

FASEB Bioadv

Critical cysteines in the functional interaction of adenylyl cyclase isoform 6 with Gαs.

Authors - Anjali Y Bhagirath