GGT1 Polyclonal antibody, PBS Only

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• GGT1 Polyclonal antibody, PBS Only (33389-1-PBS)

• 

  WB analysis using 33389-1-AP (same clone as 33389-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 33389-1-AP (GGT1 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 33389-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse kidney using 33389-1-AP (same clone as 33389-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using 33389-1-AP (GGT1 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 33389-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse kidney using 33389-1-AP (same clone as 33389-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using 33389-1-AP (GGT1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 33389-1-PBS in a different storage buffer formulation.

GGT1 Polyclonal Antibody for WB, IHC, Indirect ELISA

Cat No. 33389-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, IHC, Indirect ELISA

Synonyms

CD224, D22S672, D22S732, GGT, GTG

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Product Information

33389-1-PBS targets GGT1 in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  CatNo: Eg4602

  Product name: Recombinant Human GGT1 protein (rFc Tag)

  Source: mammalian cells-derived, pHZ-KIsec-N-rFc

  Tag: N-rFc

  Domain: 27-569 aa of BC025927

  Sequence: PSASKEPDNHVYTRAAVAADAKQCSKIGRDALRDGGSAVDAAIAALLCVGLMNAHSMGIGGGLFLTIYNSTTRKAEVINAREVAPRLAFATMFNSSEQSQKGGLSVAVPGEIRGYELAHQRHGRLPWARLFQPSIQLARQGFPVGKGLAAALENKRTVIEQQPVLCEVFCRDRKVLREGERLTLPQLADTYETLAIEGAQAFYNGSLTAQIVKDIQAAGGIVTAEDLNNYRAELIEHPLNISLGDVVLYMPSAPLSGPVLALILNILKGYNFSRESVESPEQKGLTYHRIVEAFRFAYAKRTLLGDPKFVDVTEVVRNMTSEFFAAQLRAQISDDTTHPISYYKPEFYTPDDGGTAHLSVVAEDGSAVSATSTINLYFGSKVRSPVSGILFNNEMDDFSSPSITNEFGVPPSPANFIQPGKQPLSSMCPTIMVGQDGQVRMVVGAAGGTQITTATALAIIYNLWFGYDVKRAVEEPRLHNQLLPNVTTVERNIDQAVTAALETRHHHTQIASTFIAVVQAIVRTAGGWAAASDSRKGGEPAGY

• Full Name: gamma-glutamyltransferase 1
• Observed Molecular Weight: 61 kDa
• GenBank Accession Number: BC025927
• Gene Symbol: GGT1
• Gene ID (NCBI): 2678
• RRID: AB_3742958
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity Purification
• UNIPROT ID: P19440
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

GGT1 is a transpeptidase whose activity increases the availability of amino acids, primarily cysteine, for intracellular GSH synthesis. GGT1 also plays a critical role in maintaining GSH homeostasis and defense against oxidative stress. In liver and obstructive biliary diseases, circulating GGT1 activity has widely been used for diagnosis purposes, as well as an indicator of alcohol consumption. (PMID: 31151999)