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  • KD/KO Validated

GNG2 Polyclonal antibody

GNG2 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

mouse, rat, human

Applications

WB, IHC, ELISA

Conjugate

Unconjugated

Cat no : 11693-1-AP

Synonyms

G gamma I, GNG2



Tested Applications

Positive WB detected inmouse brain tissue, rat brain tissue

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:1000-1:6000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

11693-1-AP targets GNG2 in WB, IHC, ELISA applications and shows reactivity with mouse, rat, human samples.

Tested Reactivity mouse, rat, human
Cited Reactivityhuman, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen GNG2 fusion protein Ag2307
Full Name guanine nucleotide binding protein (G protein), gamma 2
Calculated Molecular Weight 71 aa, 8 kDa
Observed Molecular Weight 8 kDa
GenBank Accession NumberBC020774
Gene Symbol GNG2
Gene ID (NCBI) 54331
RRIDAB_2263277
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Gγ2 subunit (Gng2/GNG2) is one of subunits of the Gβγ-dimer composing heterotrimeric G protein with a Gα-subunit. Heterotrimeric G protein has been reported to be involved in various biological activities including cell proliferation, differentiation, invasion and angiogenesis. It is expressed in a range of foetal tissues as well as adult testis, adrenal gland, brain, white blood cells and lung.

Protocols

Product Specific Protocols
WB protocol for GNG2 antibody 11693-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
human,mouseWB,IHC

Am J Cancer Res

Reduced GNG2 expression levels in mouse malignant melanomas and human melanoma cell lines.

Authors - Yajima Ichiro I
humanWB

Am J Cancer Res

GNG2 inhibits invasion of human malignant melanoma cells with decreased FAK activity.

Authors - Ichiro Yajima
  • KD Validated
humanWB

J Dermatol Sci

Functional analysis of GNG2 in human malignant melanoma cells.

Authors - Yajima Ichiro I