Product Information
31846-1-PBS targets GPR158 in WB, Indirect ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag34602 Product name: Recombinant human GPR158 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 24-417 aa of BC157124 Sequence: ASRDPQGRPDSPRERTPKGKPHAQQPGRASASDSSAPWSRSTDGTILAQKLAEEVPMDVASYLYTGDSHQLKRANCSGRYELAGLPGKWPALASAHPSLHRALDTLTHATNFLNVMLQSNKSREQNLQDDLDWYQALVWSLLEGEPSISRAAITFSTDSLSAPAPQVFLQATREESRILLQDLSSSAPHLANATLETEWFHGLRRKWRPHLHRRGPNQGPRGLGHSWRRKDGLGGDKSHFKWSPPYLECENGSYKPGWLVTLSSAIYGLQPNLVPEFRGVMKVDINLQKVDIDQCSSDGWFSGTHKCHLNNSECMPIKGLGFVLGAYECICKAGFYHPGVLPVNNFRRRGPDQHISGSTKDVSEEAYVCLPCREGCPFCADDSPCFVQEDKYLR Predict reactive species |
| Full Name | G protein-coupled receptor 158 |
| Calculated Molecular Weight | 135 kDa |
| Observed Molecular Weight | 150 kDa |
| GenBank Accession Number | BC157124 |
| Gene Symbol | GPR158 |
| Gene ID (NCBI) | 57512 |
| RRID | AB_3670127 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity Purification |
| UNIPROT ID | Q5T848 |
| Storage Buffer | PBS only, pH 7.3. |
| Storage Conditions | Store at -80°C. |
Background Information
G protein-coupled receptors (GPCR) are the largest family of proteins encoded in mammalian genomes that detect extracellular signals to program cellular response, which are essential to understanding physiology, disease, and drug development (PMID: 29249361; 29298813). G protein-coupled receptor 158 (GPR158, also known as mGlyR) is a class C orphan GPCR prominently expressed in brain tissue, where it controls synapse formation and function (PMID: 22689652; 34793198). It can transduce signals by coupling to the regulator of protein signaling (RGS) proteins and be related to the development of major depressive disorder and prostate cancer (PMID: 36996198; 29419376; 25693195).
