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- KD/KO Validated
GPX7 Polyclonal antibody
GPX7 Polyclonal Antibody for IHC, WB, ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human and More (2)
Applications
WB, IHC, IF, ELISA
Conjugate
Unconjugated
Cat no : 13501-1-AP
Synonyms
Validation Data Gallery
Tested Applications
Positive WB detected in | human liver tissue, human placenta tissue, human brain tissue, Transfected HEK-293 cells |
Positive IHC detected in | human liver cancer tissue, human brain tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
Recommended dilution
Application | Dilution |
---|---|
Western Blot (WB) | WB : 1:500-1:2000 |
Immunohistochemistry (IHC) | IHC : 1:50-1:500 |
Sample-dependent, check data in validation data gallery |
Published Applications
KD/KO | See 3 publications below |
WB | See 10 publications below |
IHC | See 3 publications below |
IF | See 1 publications below |
Product Information
13501-1-AP targets GPX7 in WB, IHC, IF, ELISA applications and shows reactivity with human samples.
Tested Reactivity | human |
Cited Reactivity | human, mouse, chicken |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | GPX7 fusion protein Ag4328 |
Full Name | glutathione peroxidase 7 |
Calculated molecular weight | 187 aa, 21 kDa |
Observed molecular weight | 18-21 kDa |
GenBank accession number | BC032788 |
Gene symbol | GPX7 |
Gene ID (NCBI) | 2882 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
GPX7(Glutathione peroxidase 7) is also named as GPX6,CL683,GSHPx-7 and belongs to the glutathione peroxidase family.It shares approximately 45% amino acid sequence with other GPX family members.Because GPX7 expression protected cells from acidic bile acidinduced DNA damage, it may protect oesophageal epithelial cells from acidic bile acid-induced apoptosis(PMID:22157330). This antibody can ve detected as 18-21kDa due to signal peptide splicing.
Protocols
Product Specific Protocols | |
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WB protocol for GPX7 antibody 13501-1-AP | Download protocol |
IHC protocol for GPX7 antibody 13501-1-AP | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |
Publications
Species | Application | Title |
---|---|---|
Oncotarget Glutathione peroxidase 7 suppresses cancer cell growth and is hypermethylated in gastric cancer. | ||
Poult Sci The development of antioxidant system in the intestinal tract of broiler chickens. | ||
J Cancer Glutathione Peroxidase 7 Suppresses Bile Salt-Induced Expression of Pro-Inflammatory Cytokines in Barrett's Carcinogenesis. | ||
J Cell Mol Med GPX7 Facilitates BMSCs Osteoblastogenesis via ER Stress and mTOR Pathway.
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Front Oncol GPX7 Is Targeted by miR-29b and GPX7 Knockdown Enhances Ferroptosis Induced by Erastin in Glioma.
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