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GREM1/Gremlin 1 Polyclonal antibody

GREM1/Gremlin 1 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, ELISA

GREM1, Cell proliferation-inducing gene 2 protein, CKTSF1B1, DAN domain family member 2, DAND2

Formulation:  PBS, Azide, Glycerol
PBS, Azide, Glycerol
Conjugate:  Unconjugated
Unconjugated
Size/Concentration: 
SKU: 

-/ -

Freight/Packing: -

Quantity

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What's the best dilution for GREM1/Gremlin 1 in ?

Tested Applications

Positive WB detected inmouse colon tissue, mouse small intestine tissue, rat colon tissue, rat small intestine tissue

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:500-1:1000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

18024-1-AP targets GREM1/Gremlin 1 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivitymouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen

CatNo: Ag12588

Product name: Recombinant human GREM1 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 18-184 aa of BC093778

Sequence: LLPAAEGKKKGSQGAIPPPDKAQHNDSEQTQSPQQPGSRNRGRGQGRGTAMPGEEVLESSQEALHVTERKYLKRDWCKTQPLKQTIHEEGCNSRTIINRFCYGQCNSFYIPRHIRKEEGSFQSCSFCKPKKFTTMMVTLNCPELQPPTKKKRVTRVKQCRCISIDLD

Predict reactive species
Full Name gremlin 1, cysteine knot superfamily, homolog (Xenopus laevis)
Calculated Molecular Weight 184 aa, 21 kDa
Observed Molecular Weight 21 kDa
GenBank Accession NumberBC093778
Gene Symbol GREM1
Gene ID (NCBI) 26585
RRIDAB_3669288
Conjugate Unconjugated
FormLiquid
Purification MethodAntigen affinity purification
UNIPROT IDO60565
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Protocols

Product Specific Protocols
WB protocol for GREM1/Gremlin 1 antibody 18024-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

What published studies show

The GREM1/Gremlin 1 Polyclonal antibody (Cat# 18024-1-AP) has 2 citations. These appear in International Journal of Molecular Sciences and Journal of Cardiovascular Pharmacology. The research fields span radiation-induced bone injury and osteoblast biology, as well as cardiovascular pharmacology involving neutrophil-mediated endothelial injury in coronary artery disease with type 2 diabetes mellitus through the GREM1-Smad signaling axis.

SpeciesApplicationTitle
mouseWB

Int J Mol Sci

Phenylethanoid Glycosides from Cistanche tubulosa (Schenk) Wight Improve Radiation-Induced Bone Injury and Reduce Grem1 Expression in Osteoblasts.

Authors - Xiaoqiang Wang

J Cardiovasc Pharmacol

SGLT2 Inhibitors Attenuate Neutrophil-Mediated Endothelial Injury in Coronary Artery Disease With Type 2 Diabetes Mellitus Through a GREM1-Associated Smad Signaling Axis.

Authors - Wenyuan Zheng
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