GYPC Recombinant monoclonal antibody, PBS Only

• 

  WB analysis using 86574-1-RR (same clone as 86574-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 86574-1-RR (GYPC antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86574-1-PBS in a different storage buffer formulation.

GYPC Uni-rAb^® Recombinant Antibody for WB, Indirect ELISA

Cat No. 86574-1-PBS

Clone No.251100D5

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, Indirect ELISA

Synonyms

CD236, CD236R, GE, GLPC, Glycoconnectin

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Product Information

86574-1-PBS targets GYPC in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen:

  CatNo: Eg4905

  Product name: Recombinant Human GYPC protein (rFc Tag)

  Source: mammalian cells-derived, pHZ-KIsec-C-rFc

  Tag: C-rFc

  Domain: 1-57 aa of BC104246

  Sequence: MWSTRSPNSTAWPLSLEPDPGMASASTTMHTTTIAEPDPGMSGWPDGRMETSTPTIM

• Full Name: glycophorin C (Gerbich blood group)
• Calculated Molecular Weight: 14 kDa
• Observed Molecular Weight: 35-40 kDa
• GenBank Accession Number: BC104246
• Gene Symbol: GYPC
• Gene ID (NCBI): 2995
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: P04921
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

Glycophorin-C, encoded by the GYPC gene, is a minor sialoglycoprotein in human erythrocyte membranes. Glycophorin-C interacts with protein 4.1R (EPB41) and plays an important role in regulating the mechanical stability of red cells. Glycophorin C acts as the receptor for the Plasmodium falciparum erythrocyte binding ligand PfEBP-2 (baebl). Glycophorin-D, also encoded by the GYPC gene, is now known as a variant of Glycophorin-C. This antibody is raised against the full-length protein of human Glycophorin-C. The apparent molecular weight of Glycophorin-C is larger than the calculated molecular weight due to glycosylation.