Product Information
17228-1-PBS targets Granzyme H in WB, Indirect ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag11069 Product name: Recombinant human GZMH protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-246 aa of BC027974 Sequence: MQPFLLLLAFLLTPGAGTEEIIGGHEAKPHSRPYMAFVQFLQEKSRKRCGGILVRKDFVLTAAHCQGSSINVTLGAHNIKEQERTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKWTTAVRPLRLPSSKAQVKPGQLCSVAGWGYVSMSTLATTLQEVLLTVQKDCQCERLFHGNYSRATEICVGDPKKTQTGFKGDSGGPLVCKDVAQGILSYGNKKGTPPGVYIKVSHFLPWIKRTMKRL Predict reactive species |
| Full Name | granzyme H (cathepsin G-like 2, protein h-CCPX) |
| Calculated Molecular Weight | 246 aa, 27 kDa |
| Observed Molecular Weight | ~30 kDa |
| GenBank Accession Number | BC027974 |
| Gene Symbol | Granzyme H |
| Gene ID (NCBI) | 2999 |
| RRID | AB_3085518 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | P20718 |
| Storage Buffer | PBS only, pH 7.3. |
| Storage Conditions | Store at -80°C. |
Background Information
Granzyme H (GzmH) belongs to a family of 5 human serine proteases that are expressed by cytotoxic immune effector cells. It's regarded as an orphan granzyme with unknown biologic functions in immune defense cells. It's reported that this serine protease is predominantly expressed at high levels in natural killer (NK) cells and has chymotrypsin-like (chymase) activity. The calculated molecular weight is 27 kDa, 17228-1-AP can detect a band around 30 kDa. (PMID: 17409270)
