HEXIM1 Monoclonal antibody
HEXIM1 Monoclonal Antibody for WB, ELISA
Host / Isotype
Mouse / IgM
Cat no : 66311-1-Ig
|Positive WB detected in
|human testis tissue, MCF-7 cells
|Western Blot (WB)
|WB : 1:500-1:2000
|It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
|Sample-dependent, check data in validation data gallery
66311-1-Ig targets HEXIM1 in WB applications and shows reactivity with human samples.
|Host / Isotype
|Mouse / IgM
|HEXIM1 fusion protein Ag8019
|hexamethylene bis-acetamide inducible 1
|Calculated molecular weight
|Observed molecular weight
|GenBank accession number
|Gene ID (NCBI)
|Thiophilic affinity chromatograph
|PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
|Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.
HEXIM1, also named CLP1, EDG1, HIS1 or MAQ1, is best known as the inhibitor of positive transcription elongation factor b, which regulates the transcription elongation of RNA polymerase II and controls 60-70% of mRNA synthesis. HEXIM1 regulates NF-kappa-B, ESR1, NR3C1 and CIITA-dependent transcriptional activity. Previous studies showed that HEXIM1 interacts with two key p53 regulators, nucleophosmin and HDM2, implying a possible connection between HEXIM1 and the p53 signaling pathway.The mainstream MW of this protein is 65-70 kDa and 54 kDa ( PMID: 33627647, PMID: 20976203, PMID: 28254838).